![]() His neurological and fundoscopic examination were normal. On examination, his body temperature was 37.2 ☌, with blood pressure 140/80 mmHg, a heart rate 84 beats/min, and respiratory rate 24 breaths/min. In December 2016, a 59-year-old man who had suffered from headaches, slowdown in speech, inability to walk, and weakness was admitted to the hospital. During the therapy, although hydrocephaly emerged, the patient was recovered without sequelae. We describe an immunocompetent man with cryptococcal meningitis (CM) who presented with multiple cerebral infarcts and cryptococcomas. Despite the low frequency in immunocompetent patients, its mortality is high due to delayed or misdiagnosis. In such cases, exposure to organisms with increased pathogenicity or undiagnosed immune deficiency may be the reason. neoformans may be rarely seen in immunocompetent individuals and the disease may occur with nonspecific symptoms that last for weeks. Although the mechanism is not fully understood, CNS infection caused by C. neoformans infections, such as advanced HIV/AIDS, idiopathic CD4+ lymphopenia, diabetes mellitus, organ transplantation, and prolonged corticosteroid usage. The immunosuppressive conditions are major risk factors for C. Additionally, skin, eyes, bones, and soft tissue may be affected. The fungus is usually acquired by inhalation from the environment, and it may disseminate hematogenously to the central nervous system (CNS). Cryptococcosis is an infection caused by the fungi Cryptococcus neoformans and gattii. Cryptococcus neoformans is an opportunistic fungus commonly seen in the environment.
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